NF-κB-IN-8 [CAS 2924565-59-1]

NF-κB-IN-8 competitively antagonizes LPS binding to MD-2. NF-κB-IN-8 reduces the expression of inflammatory factors by binding to MD-2. NF-κB-IN-8 also inhibits ALP activity. NF-κB-IN-8 can be used for the research of inflammation such as acute lung injury (ALI) [1].

[2924565-59-1]

C24H21N3O3

399.44

COC1=CC=CC(COC2=CC=C(C=C2)/C=C/C(NC3=NC4=C(N3)C=CC=C4)=O)=C1

NF-κB

10 mM in DMSO

Room temperature