NFh-ALP

NFh-ALP is an alkaline phosphatase (ALP) -activatable photosensitizer. NFh-ALP could be activated by ALP in cells and generate 1O2 under 808 nm excitation, effectively killing tumor cells by inducing apoptosis and having good biocompatibility. The maximum absorption wavelength of NFh-ALP is about 656 nm[1].

C27H27Br2INO5P

763.19

CC1(C)C(/C=C/C(CCC2)=C3C2=CC(C=C(Br)C(OP(O)(O)=O)=C4)=C4O3)=[N+](CC)C5=CC=C(Br)C=C15.[I-]

Phosphatase

Room temperature