NGFR, Mouse (HEK293, Fc)

Nerve Growth Factor Receptor (NGFR) also known as CD271, p75NTR, TNFRSF16, is a transmembrane low-affinity receptor for the neurotrophin family. NGFR has no intrinsic tyrosine kinase activity. NGFR can act as a tumour suppressor, negatively regulating cell growth and proliferation[1]. NGF-NGFR cascade activates NF-κB, leading to inhibition of apoptosis, increases survival of schwannoma, and breast cancer cells[3]. NGFR Protein, Mouse (HEK293, Fc) is a recombinant protein with a C-Terminal Fc label, It consists of 243 amino acids and is produced in HEK293 cells.

18053 (Gene_ID) Q9Z0W1 (M1-N243) (Accession)

93.6

Stored at -20°C for 2 years

Room temperature in continental US; may vary elsewhere.