NH2-PEG3-VC-PAB-MMAE [CAS 2641442-97-7]

NH2-PEG3-VC-PAB-MMAE is a drug-linker conjugate for ADC, consisting of a cleavable ADC linker (NH2-PEG3-VC-PAB) and a potent tubulin inhibitor Monomethyl auristatin E (MMAE). NH2-PEG3-VC-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs).

[2641442-97-7]

C66H109N11O16

1312.64

O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(COCCOCCOCCN)=O)=O)=O)=O)=O)=O)=O)OC)=O

Drug-Linker Conjugates for ADC; Microtubule/Tubulin

99.1

DMSO : 90 mg/mL (ultrasonic)

-20°C (Powder, sealed storage, away from moisture and light)

Blue Ice