NIR-FP is a near-infrared fluorescent probe with high sensitivity and selectivity for superoxide anion O2-. O2- is the main precursor of ROS, and ferroptosis-mediated epilepsy models can be dynamically tracked by detecting O2-. Ferroptosis-mediated epilepsy models include: kainic acid -induced chronic epilepsy model, Pentylenetetrazole-induced acute epilepsy model, and pilocarpine (HY-B0726A) -induced epilepsy model[1].
