Niravoline [CAS 130610-93-4]

Niravoline (RU51599) is an arginine vasopressin (AVP) release inhibitor and a selective kappa opioid receptor agonist. Niravoline has a pure water diuresis effect without associated electrolyte excretion. Niravoline can reduce brain oedema following transient forebrain ischaemia in rats[1].

[130610-93-4]

C22H25N3O3

379.45

O=C(N([C@@H]1[C@@H](N2CCCC2)CC3=C1C=CC=C3)C)CC4=CC=CC([N+]([O-])=O)=C4

Opioid Receptor; Vasopressin Receptor

κ Opioid Receptor/KOR

Room temperature