Nisoldipine-d3

Nisoldipine-d3 is deuterated labeled Nisoldipine. Nisoldipine (BAY-k 5552; Sular) is a highly efficient and specific L-type Cav1.2 channel blocker with an IC50 of 10 nM.

C20H21D3N2O6

391.43

O=C(C1=C(C)NC(C)=C(C(OCC(C)C)=O)C1C2=CC=CC=C2[N+]([O-])=O)OC([2H])([2H])[2H]

Calcium Channel; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS)

10 mM in DMSO

Room temperature