NLRP3-IN-15 [CAS 2767369-71-9]

NLRP3-IN-15 is a potent and selective NLRP3 inflammasome inhibitor. NLRP3-IN-15 inhibits IL-1β release with an IC50 of 0.114 μM. NLRP3-IN-15 can be used for the research of inflammation[1].

[2767369-71-9]

C22H19NO4

361.39

CC1=C2C=CC3=C(C2=CC=C1)C(C(C4=C3OC5=C4CCN(C5)CCO)=O)=O

NOD-like Receptor (NLR)

NLRP3

10 mM in DMSO

Room temperature