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SKU:QM-0151083-01
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NLRP3-IN-17 is a potent, selective and orally active NLRP3 inflammasome inhibitor with an IC50 value of 7 nM. NLRP3-IN-17 significantly inhibits NLRP3 dependent IL-1β secretion in mice and can be used for chronic inflammatory diseases research[1].
[2254432-75-0]
C21H22N4O2S
394.49
N#CN=S(NC(NC1=C(CCC2)C2=CC3=C1CCC3)=O)(C4=CC=C(C)C=C4)=O
NOD-like Receptor (NLR)
NLRP3
10mM
99.23
DMSO : 33.33 mg/mL (ultrasonic)
4°C (Powder, sealed storage, away from moisture)
Room Temperature
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NLRP3-IN-17 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.