NLRP3-IN-73

NLRP3-IN-73 (W16) is an orally active inhibitor of the assembly of NLRP3 inflammasome via targeting NLRP3, with an IC50 value of 0.18 μM for the NLRP3/IL-1β pathway[1].

C26H22FN3O3

443.47

CC[C@H](NC(C1=C(C)C(C2=CC=CC(F)=C2)=NC3=C1C=CC=C3[N+]([O-])=O)=O)C4=CC=CC=C4

NOD-like Receptor (NLR)

Room temperature