NNRT-IN-10 [CAS 2459751-62-1]

NNRT-IN-10 is a potent, selective and orally active non-nucleoside HIV-1 reverse transcriptase (NNRTI) inhibitor with with an EC50 values ranging from 1.16 to 18.3 nM for HIV and its mutant strains. NNRT-IN-10 exhibits good pharmacokinetic properties and favorable safety profiles. NNRT-IN-10 can be used for the study of AIDS, caused by HIV-1[1].

[2459751-62-1]

C31H32N6O3S

568.69

CC1=CC(/C=C/C#N)=CC(C)=C1OC2=C(C=CC=N3)C3=NC(NC4CCN(CC5=CC=C(S(C)(=O)=O)C=C5)CC4)=N2

Cytochrome P450; HIV; Potassium Channel; Reverse Transcriptase

CYP1A2; CYP2C19; CYP2C9; CYP2D6; HIV-1

Room temperature