NOTA-IMB-RGD
NOTA-IMB-RGD
SKU:QM-0013047
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Product Details
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Description
NOTA-IMB-RGD is a dual molecular probe targeting integrin αvβ3 and programmed death ligand-1 (PD-L1) . NOTA-IMB-RGD blocks the PD-1/PD-L1 signaling pathway and integrin αvβ3-overexpressing tumor vasculature. NOTA-IMB-RGD is promising for research of solid tumors co-expressing PD-L1 and αvβ3 (e.g., glioma, breast cancer) [1].
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Molecular Formula
C118H196N30O37S
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Molecular Weight
2659.06
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Smiles
O=C(NCCCCC(C(N[C@H](C(N[C@@H]([C@@H](C)O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C)C(N1CCC[C@H]1C(N[C@H](CC(N)=O)C(N[C@@H]([C@H](CC)C)C(N[C@@H]([C@@H](C)CC)C(N[C@H](CO)C(N[C@@H](C)C(N[C@H](C(O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O)CC(C)C)=O)CO)=O)CS)=O)=O)CC(C)C)=O)NC(CCCCNC(CN2CCN(CCN(CC2)CC(O)=O)CC(O)=O)=O)=O)COCCOCCNC(CCC(NCCCCC3NC([C@H](NC(CNC(C(NC([C@@H](NC3=O)CC4=CC=CC=C4)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)=O)=O
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Target
Integrin; PD-1/PD-L1
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Shipping Conditions
Room temperature
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NOTA-IMB-RGD
NOTA-IMB-RGD is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.