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NP10679 [CAS 2914889-88-4]

NP10679 [CAS 2914889-88-4]

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QM-0149892-01

£148.75 GBP
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Product Details

  • Description

    NP10679 is a selective, pH dependent GluN2B subunit-specific N-methyl-D-aspartate (NMDA) receptor inhibitor with high oral bioavailability and good brain penetration. NP10679 inhibits GluN2B with IC50s of 23 and 142 nM at pH 6.9 and 7.6, respectively. NP10679 is a histamine H1 antagonist and a hERG channel inhibitor with IC50s of 73 and 620 nM, respectively. NP10679 is a reversible inhibitor of human liver CYP enzymes[1].

  • CAS Number

    [2914889-88-4]

  • Molecular Formula

    C23H26F3N3O3

  • Molecular Weight

    449.47

  • Smiles

    O=C(N1)CCC2=C1C=CC(OC[C@H](O)CN(CC3)CCN3C4=CC=C(C(F)(F)F)C=C4)=C2

  • Target

    Adrenergic Receptor; Cytochrome P450; Histamine Receptor; iGluR; Potassium Channel

  • Isoform

    H1 Receptor; α adrenergic receptor

  • Concentration

    10mM

  • Purity

    98.4

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
10 mM - 1 mLQM-0149892-01
10 mM - 1 mLQM-0149892-01
£148.75/ea		 £0.00
£148.75/ea £0.00
5 mgQM-0149892-02
5 mgQM-0149892-02
£149.88/ea		 £0.00
£149.88/ea £0.00
10 mgQM-0149892-03
10 mgQM-0149892-03
£265.06/ea		 £0.00
£265.06/ea £0.00
25 mgQM-0149892-04
25 mgQM-0149892-04
£501.98/ea		 £0.00
£501.98/ea £0.00
50 mgQM-0149892-05
50 mgQM-0149892-05
£772.92/ea		 £0.00
£772.92/ea £0.00
100 mgQM-0149892-06
100 mgQM-0149892-06
£1,209.11/ea		 £0.00
£1,209.11/ea £0.00
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NP10679 [CAS 2914889-88-4]

NP10679 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.