NPB-1575 [CAS 161984-54-9]

NPB-1575 is a potent, orally active and brain-penetrant anti-inflammatory agent. NPB-1575 mitigates neuroinflammation and resists ferroptosis by activating the IRS2/Nrf2/NF-κB axis. NPB-1575 shows protective effect against cerebral ischemic injury and improves the neurological functional prognosis. NPB-1575 can be used for the study of ischemic stroke[1].

[161984-54-9]

C19H22O4

314.38

OC1=CC(O)=C(C/C=C(C)/C)C(CCC2=CC(O)=C(O)C=C2)=C1

Ferroptosis; FOXO; Keap1-Nrf2; NF-κB; NO Synthase; Quinone Reductase

Room temperature