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NPS-2143 [CAS 284035-33-2]

NPS-2143 [CAS 284035-33-2]

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SKU:QM-0079072-01

£94.75 GBP
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  • Description

    NPS-2143 (SB-262470A), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor[1][2].

  • CAS Number

    [284035-33-2]

  • Molecular Formula

    C24H25ClN2O2

  • Molecular Weight

    408.92

  • Smiles

    N#CC1=C(OC[C@@H](CNC(C)(CC2=CC=C3C=CC=CC3=C2)C)O)C=CC=C1Cl

  • Target

    CaSR

  • Purity

    99.94

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H315, H319, H320

  • Precautions

    H315, H319, H320

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Variant Variant total Quantity Price Variant total
5 mgQM-0079072-01
5 mgQM-0079072-01
£94.75/ea
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10 mgQM-0079072-02
10 mgQM-0079072-02
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50 mgQM-0079072-03
50 mgQM-0079072-03
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100 mgQM-0079072-04
100 mgQM-0079072-04
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500 mgQM-0079072-05
500 mgQM-0079072-05
£1,806.89/ea
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1 gQM-0079072-06
1 gQM-0079072-06
£2,861.51/ea
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NPS-2143 [CAS 284035-33-2]

NPS-2143 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.