NPT100-18A

NPT100-18A is an αSyn oligomerization inhibitor. NPT10018A rescues cleaved caspase-3 levels to control levels. NPT10018A attenuates mitochondrial oxidative stress probe levels in a compartment-specific manner and, at higher concentrations, increases ATP signals. NPT100-18A can be used for the study of Parkinson’s disease (PD) [1][2].

C28H39N5O3

493.64

O=C1N(CC2CCNCC2)CC(N(C(CCC3=CNC4=C3C=CC=C4)=O)CCC5=O)N5C1CCCC

Caspase; Reactive Oxygen Species (ROS) ; α-synuclein

Caspase 3

Room temperature