NR2F2-IN-1 (free base) [CAS 452087-38-6]

NR2F2-IN-1 (free base) is a potent and selective orphan nuclear receptor COUP-TFII (NR2F2) inhibitor. NR2F2-IN-1 (free base) substantially inhibits COUP-TFII–driven NGFIA reporter expression. NR2F2-IN-1 (free base) directly binds to the COUP-TFII ligand-binding domain and disrupts COUP-TFII interaction with transcription regulators, including FOXA1, thus repressing COUP-TFII activity on target gene regulation[1].

[452087-38-6]

C17H19N3O2S

329.42

COC(C(OC)=C1)=CC=C1CCNC2=C3C=C(C)SC3=NC=N2

Orphan Nuclear Receptor; Orphan Receptor

99.34

DMSO : 125 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature