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Nrf2 degrader 1 [CAS 3025286-00-1]

Nrf2 degrader 1 [CAS 3025286-00-1]

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SKU:QM-0153336-01

£1,116.77 GBP
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  • Description

    Nrf2 degrader 1 (compound 1) is a PROTAC Nrf2 degrader with anticancer effects. Nrf2 degrader 1 inhibits cancer cells growth for A549 and LK-2 cells with IC50 values of 100 nM and 40 nM, respectively[1].

  • CAS Number

    [3025286-00-1]

  • Molecular Formula

    C45H42N6O8S

  • Molecular Weight

    826.92

  • Smiles

    O=C1NC(C(N2C(C(C(NCCOCCOC3=CC(CC(NC4=NC(C5=CC=C(N(C(C6=C(C)C=CC=C6)=O)CC7)C7=C5)=C(C)S4)=O)=CC=C3)=CC=C8)=C8C2=O)=O)CC1)=O

  • Target

    Keap1-Nrf2; PROTACs

  • Purity

    99.12

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

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5 mgQM-0153336-01
5 mgQM-0153336-01
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10 mgQM-0153336-02
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25 mgQM-0153336-03
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50 mgQM-0153336-04
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100 mgQM-0153336-05
100 mgQM-0153336-05
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Nrf2 degrader 1 [CAS 3025286-00-1]

Nrf2 degrader 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.