OB-24 is a selective small-molecule HO-1 inhibitor (IC50 = 1.9 μM for HO-1 and IC50 for HO-2 >100 μM) . OB-24 possesses anti-tumor and anti-metastatic properties. OB-24 can be studies in research such as prostate cancer, melanoma, ovarian carcinoma and lung metastasis[1][2].
CAS Number
[939825-12-4]
Molecular Formula
C15H18BrClN2O2
Molecular Weight
373.67
Smiles
BrC1=CC=C(CCC2(CN3C=CN=C3)OCCO2)C=C1.Cl
Target
Heme Oxygenase (HO) ; Reactive Oxygen Species (ROS)
Isoform
HO-1; HO-2
Purity
98.21
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)