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Obatoclax [CAS 803712-67-6]

Obatoclax [CAS 803712-67-6]

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QM-0058153

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Product Details

  • Description

    Obatoclax (GX15-070), a BH3 mimetic, is a pan-BCL-2 family proteins inhibitor with a Ki of 220 nM for BCL-2[1][2]. Obatoclax induces autophagy-dependent cell death and targets cyclin D1 for proteasomal degradation. Obatoclax has anti-cancer and broad-spectrum antiparasitic activity[3][4].

  • CAS Number

    [803712-67-6]

  • Molecular Formula

    C20H19N3O

  • Molecular Weight

    317.38

  • Smiles

    COC1=CC(C(N2)=CC3=C2C=CC=C3)=N/C1=C\C4=C(C)C=C(C)N4

  • Target

    Autophagy; Bcl-2 Family; Parasite

  • Isoform

    Bcl-2; Bcl-B; Bcl-W; Bcl-xL; Mcl-1

  • Purity

    99

  • Solubility

    10 mM in DMSO

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Obatoclax [CAS 803712-67-6]

Obatoclax is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.