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Octyl-α-ketoglutarate [CAS 876150-14-0]
Octyl-α-ketoglutarate [CAS 876150-14-0]
SKU:QM-0138384-01
£200.66 GBP
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Product Details
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Description
Octyl-α-ketoglutarate (1-Octyl 2-oxopentanedioate) is a stable, cell-permeable form of α-ketoglutarate which accumulates rapidly in HEK293 cells with a dysfunctional tricarboxylic acid (TCA) cycle, stimulating prolyl hydroxylase (PHD) activity. In addition, Octyl-α-ketoglutarate competitively blocks succinate- or fumarate-mediated inhibition of PHD[1].
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CAS Number
[876150-14-0]
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Molecular Formula
C13H22O5
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Molecular Weight
258.31
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Smiles
O=C(OCCCCCCCC)C(CCC(O)=O)=O
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Target
HIF/HIF Prolyl-Hydroxylase
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Concentration
38.71 mM * 100 μL in Methyl acetate
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Purity
99.9
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Storage Conditions
Solution, -20°C, 2 years
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Shipping Conditions
Blue Ice
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Hazard Statement
H225, H319, H336
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Precautions
H225, H319, H336
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Octyl-α-ketoglutarate [CAS 876150-14-0]
Octyl-α-ketoglutarate is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.