Odevixibat-d5

Odevixibat-d5 is deuterated labeled Odevixibat. Odevixibat (A4250) is a selective and orally active ileal apical sodium-dependent bile acid transporter (ASBT) inhibitor. Odevixibat decreases cholestatic liver and bile duct injury in mice model. Odevixibat has the potential for the treatment of primary biliary cirrhosis[1].

C37H43D5N4O8S2

745.96

[2H]C1=C(C([2H])=C(C([2H])=C1[2H])N2CC(CCCC)(NS(=O)(C3=CC(OCC(N[C@H](C4=CC=C(C=C4)O)C(N[C@H](C(O)=O)CC)=O)=O)=C(C=C32)SC)=O)CCCC)[2H]

Apical Sodium-Dependent Bile Acid Transporter; Isotope-Labeled Compounds

10 mM in DMSO

Room temperature