Omesdafexor [CAS 2244440-85-3]

Omesdafexor (MET642) is an oral FXR agonist. Omesdafexor can improve colitis induced by adoptive T cell transfer, promote intestinal antimicrobial function, barrier function and inhibit inflammation [1][2][3].

[2244440-85-3]

C34H43N3O3

541.72

CC(C=C1[C@@H](CC2)CC[C@H]2CN(C3=CC(C4=CN(C5CC5)N=C4)=CC=C3)C([C@@H]6CC[C@H](CC6)O)=O)=C(C=C1)OC

FXR

99.65

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature