Name: ON1231320 [CAS 1312471-39-8]
Brand: QuantiMol
SKU: QM-0079685-01
Price: 80.89 GBP
Availability: InStock

Product Details

Description
ON1231320 is a highly specific polo like kinase 2 (PLK2) inhibitor with an IC50 of 0.31 μM. ON1231320 blocks tumor cell cycle progression in the G2/M phase in mitosis, causing apoptotic cell death. ON1231320, an arylsulfonyl pyrido-pyrimidinone, has antitumor activity[1][2].
CAS Number
[1312471-39-8]
Molecular Formula
C22H15F2N5O3S
Molecular Weight
467.45
Smiles
O=C1C(S(=O)(C2=CC=C(F)C=C2F)=O)=CC3=CN=C(NC4=CC5=C(NC=C5)C=C4)N=C3N1C
Target
Apoptosis; Mitosis; Polo-like Kinase (PLK)
Isoform
PLK1; PLK2; PLK3; PLK4
Purity
99.9
Solubility
DMSO : 50 mg/mL (ultrasonic)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
1 mgQM-0079685-01	1 mgQM-0079685-01 £80.89/ea	£0.00	Quantity	£80.89/ea	£0.00

5 mgQM-0079685-02	5 mgQM-0079685-02 £188.51/ea	£0.00	Quantity	£188.51/ea	£0.00

10 mM - 1 mLQM-0079685-03	10 mM - 1 mLQM-0079685-03 £192.16/ea	£0.00	Quantity	£192.16/ea	£0.00

10 mgQM-0079685-04	10 mgQM-0079685-04 £284.50/ea	£0.00	Quantity	£284.50/ea	£0.00

25 mgQM-0079685-05	25 mgQM-0079685-05 £533.57/ea	£0.00	Quantity	£533.57/ea	£0.00

50 mgQM-0079685-06	50 mgQM-0079685-06 £809.38/ea	£0.00	Quantity	£809.38/ea	£0.00

100 mgQM-0079685-07	100 mgQM-0079685-07 £1,362.20/ea	£0.00	Quantity	£1,362.20/ea	£0.00

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ON1231320 [CAS 1312471-39-8]

ON1231320 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.