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SKU:QM-0154292-01
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Onatasertib (CC-223) is a potent, selective, and orally bioavailable inhibitor of mTOR kinase, with an IC50 value for mTOR kinase of 16 nM. Onatasertib inhibits both mTORC1 and mTORC2.
[1228013-30-6]
C21H27N5O3
397.47
O=C1CNC2=NC=C(C3=CC=C(C(C)(O)C)N=C3)N=C2N1[C@H]4CC[C@H](OC)CC4
Apoptosis; mTOR
MTOR; mTORC1; mTORC2
10mM
99.13
DMSO : ≥ 27 mg/mL
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H302, H315, H319, H335
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Onatasertib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.