ONO-4817 [CAS 223472-31-9]

ONO-4817 is a potent inhibitor of matrix metalloproteinase (MMP) . Inhibition of matrix metalloproteinases (MMPs) is expected to suppress atherosclerotic neointimal proliferation and thus limits atheromatous plaque progression. ONO-4817 suppresses the development of aortic intimal hyperplasia in experimental hyperlipidemic rabbit[1].

[223472-31-9]

C22H28N2O6

416.47

ONC([C@@H](C)C[C@@H](COCOCC)NC(C(C=C1)=CC=C1OC2=CC=CC=C2)=O)=O

MMP

98.94

DMSO : 125 mg/mL (ultrasonic) |Ethanol : 15 mg/mL (ultrasonic)

-20°C, 3 years (Powder)

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