OP-5244 [CAS 2381268-71-7]

OP-5244 is a potent and orally active inhibitor of CD73, with an IC50 of 0.25 nM. OP-5244 reverses immunosuppression through blocking of adenosine production, and has the potential for the cancer research[1].

[2381268-71-7]

C19H29ClN5O9P

537.89

O[C@H]1[C@@H](O)[C@H](N2N=CC3=C(NC4CCCC4)N=C(Cl)N=C32)O[C@@H]1CO[C@]([P](O)(O)=O)(COC)CO

CD73

99.07

DMSO : 250 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

4°C (Powder, sealed storage, away from moisture and light)

Room Temperature