Oroxylin A-7-O-glucuronide [CAS 36948-76-2]
Oroxylin A-7-O-glucuronide [CAS 36948-76-2]
SKU:QM-0164987-01
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Product Details
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Description
Oroxylin A-7-O-glucuronide (oroxyloside) is an orally active flavonoid glucuronide and metabolite of Oroxylin A. Oroxylin A-7-O-glucuronide can be extracted from the dried root of Scutellaria baicalensis. Oroxylin A-7-O-glucuronide exhibits prolyl oligopeptidase inhibitory activity. Oroxylin A-7-O-glucuronide inhibits the JNK pathway, upregulates PPARγ, and inhibits NF-κB p65 nuclear translocation. Oroxylin A-7-O-glucuronide reduces cytokine (IL-1β, IL-6) production. Oroxylin A-7-O-glucuronide exhibits anti-angiogenic, anti-tumor (glioma, liver cancer), anti-inflammatory, and hepatoprotective activities[1][2][3][4][5][6].
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CAS Number
[36948-76-2]
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Molecular Formula
C22H20O11
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Molecular Weight
460.39
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Smiles
OC1=C2C(OC(C3=CC=CC=C3)=CC2=O)=CC(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(O)=O)=C1OC
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Target
Drug Metabolite; Interleukin Related; JNK; NF-κB; PPAR; Prolyl Endopeptidase (PREP)
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Isoform
IL-1; IL-6; PPARγ
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Purity
99.83
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Solubility
DMSO : 50 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302
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Precautions
H302
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Oroxylin A-7-O-glucuronide [CAS 36948-76-2]
Oroxylin A-7-O-glucuronide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.