Orphanin FQ (1-11) [CAS 178249-41-7]

Orphanin FQ (1-11), a orphanin FQ or nociceptin (OFQ/N) fragment, is a potent NOP receptor (ORL-1; OP4) agonist, with a Ki of 55 nM. Orphanin FQ (1-11) has no affinity for μ, δ, κ1 and κ3 receptors (Ki>1000 nM) . Orphanin FQ (1-11) is analgesic in CD-1 mice[1][2].

[178249-41-7]

C49H75N15O14

1098.21

O=C(NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC2=CC=CC=C2)N

Opioid Receptor

NOP Receptor/ORL1

99.52

H2O : ≥ 100 mg/mL

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Blue Ice