OSMI-3 [CAS 2260791-13-5]

OSMI-3 (Compound 2b) is a potent, long-lasting, and cell-permeable O-linked N-acetylglucosamine transferase (OGT) inhibitor. Cells contain a large nuclear pool of partially spliced OGT transcript, and OSMI-3 increases detained intron splicing in cells[1].

[2260791-13-5]

C32H35N3O9S2

669.77

O=S(N[C@H](C1=CC=CC=C1OCCCC(OCC)=O)C(N(CC(OCC)=O)CC2=CC=CS2)=O)(C3=CC4=C(NC(C=C4)=O)C=C3)=O

Acyltransferase; OGT

99.08

10 mM in DMSO

-20°C, 3 years (Powder)

Blue Ice