OX04529

OX04529 (compound 69) is a potent, selective and orally active agonist of GPR84. OX04529 inhibits FSK-induced cAMP production with an EC50 of 0.0185 nM. OX04529 displayed excellent potency, high G-protein signaling bias[1].

C15H13ClF3NO2

331.72

[O-][N+]1=CC(CCCC2=CC=C(C(C(F)(F)F)=C2)Cl)=CC(O)=C1

GPR84

10 mM in DMSO

Room temperature