P-CAB agent 1 [CAS 2374139-68-9]

P-CAB agent 1 (compound B19) is a highly potent potassium-competitive acid blocker agent with an IC50 value of 60.50 nM for H+/K+-ATPase. P-CAB agent 1 has acceptable oral absorption in rats. P-CAB agent 1 can be used for researching acid-related disorders (ARDs) [1].

[2374139-68-9]

C26H23FN4O

426.49

O=C(N)C1=CC(C2=CC=CC(CN3N=C4CN(CC4=C3C5=CC=CC=C5F)C)=C2)=CC=C1

Potassium Channel

10 mM in DMSO

Room temperature