P-Ethynylphenylalanine [CAS 278605-15-5]
P-Ethynylphenylalanine [CAS 278605-15-5]
SKU:QM-0155798-01
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Product Details
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Description
P-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine) is a potent, selective, reversible and competitive inhibitor of tryptophan hydroxylase (TPH), with a Ki of 32.6 μM[1]. p-Ethynylphenylalanine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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CAS Number
[278605-15-5]
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Molecular Formula
C11H11NO2
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Molecular Weight
189.21
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Smiles
N[C@@H](CC1=CC=C(C#C)C=C1)C(O)=O
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Target
Tryptophan Hydroxylase
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Concentration
10mM
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Purity
99.93
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Solubility
1M HCl : 240 mg/mL (ultrasonic; adjust pH to 1 with HCl) |1M NaOH : 240 mg/mL (ultrasonic; adjust pH to 11 with NaOH) |DMSO : 2.22 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315, H319, H335
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Precautions
H315, H319, H335
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P-Ethynylphenylalanine [CAS 278605-15-5]
P-Ethynylphenylalanine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.