P2X7-IN-2 [CAS 1058709-63-9]

P2X7-IN-2 (compound 58) is a P2X7 receptor inhibitor. P2X7-IN-2 inhibits IL-Iβ release with an IC50 value of 0.01 nM. P2X7-IN-2 can be used for the research of autoimmunity, inflammation and cardiovascular disease[1].

[1058709-63-9]

C22H21F4N3O2

435.41

O=C(NC1=C(C)C=CC2=C1C=CN([C@H](C)CN)C2=O)CC3=CC=C(C(F)(F)F)C(F)=C3

Interleukin Related; P2X Receptor

10 mM in DMSO

Room temperature