P5 (PEG12) -VC-PAB-Exatecan [CAS 2928571-52-0]

P5 (PEG12) -VC-PAB-Exatecan (LP3) is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor Exatecan and a linker P5 (PEG24) -VC-PAB to make antibody agent conjugate (ADC). P5 (PEG12) -VC-PAB-Exatecan can be used for the research of tumor[1].

[2928571-52-0]

C76H103FN9O24P

1576.65

O=C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC(C=C1)=CC=C1COC(N[C@H]2CCC3=C4C2=C5C(C(N6C5)=CC([C@](CC)(O)C(OC7)=O)=C7C6=O)=NC4=CC(F)=C3C)=O)=O)=O)C8=CC=C(NP(C#C)(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO)=O)C=C8

Drug-Linker Conjugates for ADC; Topoisomerase

Room temperature