Palbociclib [CAS 571190-30-2]
Palbociclib [CAS 571190-30-2]
SKU:QM-0156462-01
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Product Details
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Description
Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma[1][3][4].
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CAS Number
[571190-30-2]
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Molecular Formula
C24H29N7O2
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Molecular Weight
447.53
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Smiles
O=C1C(C(C)=O)=C(C2=CN=C(N=C2N1C3CCCC3)NC4=CC=C(N5CCNCC5)C=N4)C
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Target
CDK
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Isoform
CDK4; CDK6
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Purity
99.97
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Solubility
0.1 M HCl : 25 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : 5 mg/mL (ultrasonic; adjust pH to 5 with HCl)
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H341, H361, H373, H411
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Precautions
H341, H361, H373, H411
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Palbociclib [CAS 571190-30-2]
Palbociclib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.