Palbociclib-d8 [CAS 1628752-83-9]
Palbociclib-d8 [CAS 1628752-83-9]
SKU:QM-0074389
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Product Details
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Description
Palbociclib-d8 is a deuterium labeled Palbociclib. Palbociclib is a selective and orally active CDK4 and CDK6 inhibitor with IC50s of 11 and 16 nM, respectively. Palbociclib has the potential for ER-positive and HER2-negative breast cancer research[1].
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CAS Number
[1628752-83-9]
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Molecular Formula
C24H21D8N7O2
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Molecular Weight
455.58
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Smiles
O=C1N(C2=NC(NC3=NC=C(C=C3)N4C([2H])(C([2H])(NC([2H])(C4([2H])[2H])[2H])[2H])[2H])=NC=C2C(C)=C1C(C)=O)C5CCCC5
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Target
CDK; Isotope-Labeled Compounds
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Isoform
CDK4; CDK6
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Purity
99.84
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Solubility
DMSO : 1mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 8.33 mg/mL (ultrasonic; warming; adjust pH to 3 with HCl; heat to 80°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H341, H361, H373, H411
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Precautions
H341, H361, H373, H411
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Palbociclib-d8 [CAS 1628752-83-9]
Palbociclib-d8 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.