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Palbociclib (dihydrochloride) [CAS 1831842-69-3]
Palbociclib (dihydrochloride) [CAS 1831842-69-3]
SKU:QM-0074387
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Product Details
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Description
Palbociclib (PD 0332991) dihydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib dihydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma[1][3][4].
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CAS Number
[1831842-69-3]
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Molecular Formula
C24H31Cl2N7O2
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Molecular Weight
520.45
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Smiles
[H]Cl.[H]Cl.O=C1C(C(C)=O)=C(C)C2=CN=C(NC3=NC=C(N4CCNCC4)C=C3)N=C2N1C5CCCC5
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Target
CDK
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Isoform
CDK4; CDK6
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Palbociclib (dihydrochloride) [CAS 1831842-69-3]
Palbociclib (dihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.