Palbociclib (hydrochloride) [CAS 571189-11-2]
Palbociclib (hydrochloride) [CAS 571189-11-2]
SKU:QM-0156464-01
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Product Details
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Description
Palbociclib (PD 0332991) hydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib hydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells. Palbociclib hydrochloride can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma[1][3][4].
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CAS Number
[571189-11-2]
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Molecular Formula
C24H29N7O2.37/20ClH
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Molecular Weight
514.99
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Smiles
O=C1C(C(C)=O)=C(C2=CN=C(N=C2N1C3CCCC3)NC4=CC=C(N5CCNCC5)C=N4)C.Cl.[37/20]
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Target
CDK
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Isoform
CDK4; CDK6
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Purity
99.96
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Solubility
10 mM in DMSO
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H341, H361, H373, H411
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Precautions
H341, H361, H373, H411
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Palbociclib (hydrochloride) [CAS 571189-11-2]
Palbociclib (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.