Palbociclib (monohydrochloride) [CAS 827022-32-2]
Palbociclib (monohydrochloride) [CAS 827022-32-2]
SKU:QM-0156463-01
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Product Details
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Description
Palbociclib (PD 0332991) monohydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib monohydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma[1][3][4].
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CAS Number
[827022-32-2]
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Molecular Formula
C24H30ClN7O2
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Molecular Weight
483.99
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Smiles
O=C1C(C(C)=O)=C(C)C2=CN=C(NC3=NC=C(N4CCNCC4)C=C3)N=C2N1C5CCCC5.Cl
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Target
CDK
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Isoform
CDK4; CDK6
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Purity
99.98
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Solubility
DMSO : 4.63 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : 1 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H341, H361, H373, H411
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Precautions
H341, H361, H373, H411
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Palbociclib (monohydrochloride) [CAS 827022-32-2]
Palbociclib (monohydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.