PAMP-12 (unmodified) (TFA)
PAMP-12 (unmodified) (TFA)
SKU:QM-0122962
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Product Details
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Description
PAMP-12 (unmodified) TFA is a potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM) . PAMP-12 (unmodified) is an endogenous peptide that elicit hypotension through inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells[1].
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Molecular Formula
C79H119F3N24O17
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Molecular Weight
1733.94
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Smiles
N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O)=O)CC4=CNC5=CC=CC=C45)=O)=O)=O)=O.O=C(C(F)(F)F)O
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Target
Mas-related G-protein-coupled Receptor (MRGPR)
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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PAMP-12 (unmodified) (TFA)
PAMP-12 (unmodified) (TFA) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.