Panaxytriol [CAS 87005-03-6]

Panaxytriol is an active component of ginseng. Panaxytriol inhibits the nuclear translocation of NF-κB, thereby reducing the production of pro-inflammatory factors (such as TNF-α, IL-1β, IL-6) and nitric oxide (NO) induced by LPS. Panaxytriol upregulates CYP3A4 by activating the nuclear receptor PXR/CAR. Panaxytriol improves motor dysfunction in a mouse model of brain inflammation. Panaxytriol can be used in the research of neurodegenerative diseases (such as Alzheimer's disease)[2].

[87005-03-6]

C17H26O3

278.39

CCCCCCC[C@@H](O)[C@H](O)CC#CC#C[C@H](O)C=C

Constitutive Androstane Receptor; Cytochrome P450; Interleukin Related; NF-κB; Pregnane X Receptor (PXR) ; TNF Receptor

CYP3A4; IL-1; IL-6; NF-κB

Room temperature