Paquinimod-d5

Paquinimod-d5 is a deuterated analog of Paquinimod. Paquinimod (ABR 215757) is a specific and orally active inhibitor of S100A8/S100A9. Paquinimod rescues the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice[1][2][3].

C21H17D5N2O3

355.44

O=C(N(C1=CC=CC=C1)C([2H])(C([2H])([2H])[2H])[2H])C2=C(C3=C(N(C2=O)C)C=CC=C3CC)O

Isotope-Labeled Compounds; SARS-CoV

10 mM in DMSO

Room temperature