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SKU:QM-0152953-01
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PBX-7011 TFA is a derivative of camptothecin , which inhibits expressions of the cancer related survival genes DDX5, Survivin, Mcl-1 and XIAP in cells FaDu, degrades DDX5 proteins and exhibits anticancer activity[1].
C26H22F3N3O8
561.46
O=C(O)C(F)(F)F.N[C@@H]1C2=C3C(C=C4C(OCO4)=C3CC1)=NC5=C2CN6C5=CC7=C(COC([C@]7(O)CC)=O)C6=O
Bcl-2 Family; Survivin
99.11
DMSO : 25 mg/mL (ultrasonic)
-20°C (Powder, sealed storage, away from moisture and light)
Blue Ice
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PBX-7011 (TFA) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.