PCSK9-IN-19

PCSK9-IN-19 (Compound 1) is a PCSK9 inhibitor. PCSK9-IN-19 can be used for research of high LDL-cholesterol levels and prevention of coronary artery disease[1].

C81H105ClFN15O15S2

1647.37

C[N+](CCOCCOCCC(NC[C@H](NC(CCSCC1=CC(CSCCNC2=O)=CC3=C1)=O)C(N[C@H](C)C(N[C@H](C(N[C@@H]4CC5=CN(CC6=CN3N=N6)C7=C5C=C(F)C=C7)=O)CC8=CC(C/C=C/CO[C@H]([C@@]9([H])C(N[C@H](C(N[C@H](C(N%10CCC[C@]%102C)=O)CC%11=CC=C(OC)C=C%11)=O)[C@H](O)C)=O)CC[N@@]9C4=O)=CC=C8)=O)=O)=O)(C)C.[Cl-]

PCSK9

10 mM in DMSO

Room temperature