PD-1/PD-L1-IN-17 [CAS 2851938-36-6]

PD-1/PD-L1-IN-17 (Compound P20) is a potent inhibitor of PD-1/PD-L1 with an IC50 value of 26.8 nM. PD-1/PD-L1-IN-17 is a promising lead compound for the development of inhibitors of the PD-1/PD-L1 interaction. PD-1/PD-L1-IN-17 has the potential for the research of cancer diseases[1].

[2851938-36-6]

C23H20ClN3O4

437.88

O=C([C@H](CO)NCC1=CC2=C(ON=C2NC3=CC=CC(C4=CC=CC=C4)=C3Cl)C=C1)O

PD-1/PD-L1

10 mM in DMSO

Room temperature