PD-1/PD-L1-IN-24 [CAS 2667680-33-1]

PD-1/PD-L1-IN-24 is a highly potent PD-1/PD-L1 inhibitor with IC50 value of 1.57 nM. PD-1/PD-L1-IN-24 can restore T-cell function at the cellular level by significantly elevating the IFN-γ level. PD-1/PD-L1-IN-24 has low toxicity on the PBMCs[1].

[2667680-33-1]

C34H30ClN5O6

640.08

N#CC1=CN=CC(COC2=CC(OC3=NC=NC4=C3C=CC=C4C5=CC6=C(OCCO6)C=C5)=C(C=C2CNC(CO)(CO)C)Cl)=C1

PD-1/PD-L1

10 mM in DMSO

Room temperature