PD-1/PD-L1-IN-26 [CAS 2966090-78-6]

PD-1/PD-L1-IN-26 (Compound II-14) is a potent inhibitor of PD-1/PD-L1 with an IC50 of 0.0380 μM. PD-1/PD-L1-IN-26 activates the immune microenvironment by promoting the infiltration of CD4+ T cells into tumor tissues. PD-1/PD-L1-IN-26 has the potential for the research of cancer diseases[1].

[2966090-78-6]

C43H52N4O8

752.89

CC1=C(C=CC=C1C2=CC=CC(OCCCN3CCC(CC3)CO)=C2)COC4=CC=C(C(OCC5=NN=C(O5)C6=CC=CC=C6)=C4)CNC(CO)(CO)CO

PD-1/PD-L1

10 mM in DMSO

Room temperature