PD-1/PD-L1-IN-41

PD-1/ PD-L1-in-41 (Compound 5c) is a PD-L1 and PD-1 inhibitor with IC50 value of 10.2 nM[1].

C33H32ClN3O5

586.08

CC1=C(C=CC=C1C2=CC=C3OCCOC3=C2)COC4=CC(OCC5=CC(C#N)=NC=C5)=C(CN(CCO)C)C=C4Cl

PD-1/PD-L1

10 mM in DMSO

Room temperature