PD 121373 [CAS 113457-06-0]

PD 121373 is a DNA complexing agent with antitumor activity. PD 121373 can bind tightly to DNA and RNA and inhibit the synthesis of DNA and RNA. The IC50 values of PD 121373 for inhibiting DNA and RNA synthesis in L1210 cells are 0.5 μM and 0.3 μM, respectively[1].

[113457-06-0]

C21H27N5OS

397.54

OC1=CC2=C(SC3=C(NCCN)C=CC4=C3C2=NN4CCN(CC)CC)C=C1

DNA/RNA Synthesis

Room temperature